William H. McClain | UW-Madison Halvorson Professor of Bacteriology and Molecular Biology, Emeritus

For a complete list of William H. McClain's publications please click here.

DISCOVERY OF THE rIIB PROTEIN OF T4 BACTERIOPHAGE
1. McClain WH, Champe SP. 1967. Detection of a peptide determined by the rII B cistron of phage T4. Proc Natl Acad Sci 58(3):1182-8 [more info]
2. McClain WH, Champe SP. 1970. Genetic alterations of the rII B cistron polypeptide of phage T4. Genetics 66(1):11-21 [more info]
TRANSFER RNA BIOSYNTHESIS
3. Barrell BG, Seidman JG, Guthrie C, McClain WH. 1974. Transfer RNA biosynthesis: The nucleotide sequence of a precursor to serine and proline transfer RNAs. Proc Natl Acad Sci 71(2):413-6 [more info]
4. Seidman JG, McClain WH. 1975. Three steps in conversion of large precursor RNA into serine and proline transfer RNAs. Proc Natl Acad Sci 72(4):1491-5 [more info]
5. McClain WH, Seidman JG. 1975. Genetic perturbations that reveal tertiary conformation of tRNA precursor molecules. Nature 257(5522):106-10 [more info]
6. Seidman JG, Barrell BG, McClain WH. 1975. Five steps in the conversion of a large precursor RNA into bacteriophage proline and serine transfer RNAs. J Mol Biol. 99(4):733-60 [more info]
7. Schmidt FJ, McClain WH. 1978. Transfer RNA biosynthesis. Alternate orders of ribonuclease P cleavage occur in vitro but not in vivo. J Biol Chem. 253(13):4730-8 [more info]
8. Mazzara GP, Plunkett G 3rd, McClain WH. 1982. DNA sequence of the transfer RNA region of bacteriophage T4: implications for transfer RNA synthesis. Proc. Natl. Acad. Sci. U.S.A. 78(2):889-92 PMC319909 [more info]
9. McClain WH, Guerrier-Takada C, Altman S. 1987. Model substrates for an RNA enzyme. Science 238(4826):527-30 [more info]
COMPUTATIONAL BIOLOGY AND THE AMINO ACID ACCEPTOR IDENTITY OF TRANSFER RNA
10. Atilgan T, Nicholas HB, McClain WH. 1986. A statistical method for correlating tRNA sequence with amino acid specificity. Nucleic Acids Res. 14(1):375-80 (PMC339420) [more info]
11. McClain WH, Nicholas HB. 1987. Differences between transfer RNA molecules. J. Mol. Biol. 194(4):635-42 [more info]
12. McClain WH, Foss K. 1988. Changing the identity of a tRNA by introducing a G-U wobble pair near the 3' acceptor end. Science 240(4853):793-6 [more info]
13. McClain WH, Chen YM, Foss K, Schneider J. 1988. Association of transfer RNA acceptor identity with a helical irregularity. Science 242(4886):1681-4 [more info]
14. McClain WH, Foss K, Jenkins RA, Schneider J. 1990. Nucleotides that determine Escherichia coli tRNA^Arg and tRNA^Lys acceptor identities revealed by analyses of mutant opal and amber suppressor tRNAs. Proc. Natl. Acad. Sci. U.S.A. 87(23):9260-4 (PMC55144) [more info]
15. McClain WH, Foss K, Jenkins RA, Schneider J. 1991. Rapid determination of nucleotides that define tRNA^Gly acceptor identity. Proc. Natl. Acad. Sci. U.S.A. 88(14):6147-51 (PMC52039) [more info]
16. Gabriel K, Schneider J, McClain WH. 1996. Functional evidence for indirect recognition of G·U in tRNA^Ala by alanyl-tRNA synthetase. Science 271(5246):195-7 [more info]
17. McClain WH, Gabriel K, Schneider J. 1996. Specific function of a G·U wobble pair from an adjacent helical site in tRNA^Ala during recognition by alanyl-tRNA synthetase. RNA 2(2):105-9 (PMC1369355) [more info]
18. McClain WH, Schneider J, Bhattacharya S, Gabriel K. 1998. The importance of tRNA backbone-mediated interactions with synthetase for aminoacylation. Proc. Natl. Acad. Sci. U.S.A. 95(2):460-5 (PMC18442) [more info]
19. McClain WH, Jou YY, Bhattacharya S, Gabriel K, Schneider J. 1999. The reliability of in vivo structure-function analysis of tRNA aminoacylation. J. Mol. Biol. 290(2):391-409 [more info]
20. Chang KY, Varani G, Bhattacharya S, Choi H, McClain WH. 1999. Correlation of deformability at a tRNA recognition site and aminoacylation specificity. Proc. Natl. Acad. Sci. U.S.A. 96(21):11764-9 (PMC18360) [more info]
21. Strazewski P, Biala E, Gabriel K, McClain WH. 1999. The relationship of thermodynamic stability at a G x U recognition site to tRNA aminoacylation specificity. RNA 5(11):1490-4 (PMC1369870) [more info]
22. Choi H, Otten S, Schneider J, McClain WH. 2002. Genetic perturbations of RNA reveal structure-based recognition in protein-RNA interaction. J. Mol. Biol. 324(4):573-6 [more info]
23. Choi H, Gabriel K, Schneider J, Otten S, McClain WH. 2003. Recognition of acceptor-stem structure of tRNA^Asp by Escherichia coli aspartyl-tRNA synthetase. RNA 9(4):386-93 (PMC1370406) [more info]

Publications